关于白白发展期UVB照光的问题!
论坛上都认为发展期要服用一个月的药稳定以后才能照光,但国外有文献认为发展期照光可以促进稳定期的到来,大家怎么看呢?参考文献:Int J Mol Sci. 2018 May; 19(5): 1509.
Published online 2018 May 18. doi: 10.3390/ijms19051509
PMCID: PMC5983813
PMID: 29783663
Clinical and Molecular Aspects of Vitiligo Treatments
Phototherapy is also an excellent modality to induce stability in active vitiligo. It takes around 3.5 months to induce stability as per vitiligo disease activity (VIDA) scoring (VIDA score 0) [84]. NB-UVB is more efficacious than PUVA in inducing stability and producing repigmentation in active disease. Moreover, a recent meta-analysis states that long-term NB-UVB (12 months) induced maximum (>75%) repigmentation rates. The face and neck were the sites that showed maximum repigmentation, followed by the trunk and limbs. Acral areas did not show >75% repigmentation. Greater than 50% and 75% repigmentation resp**e to NB-UVB at sites other than the face and neck did not change significantly by addition of topical vi**in D3 analogues or topical calcineurin inhibitors [83].
光疗也是诱导活动性白癜风稳定的一种极佳方式。根据白癜风疾病活动度(VIDA)评分(VIDA评分0),诱导稳定大约需要3.5个月[ 84 ]。NB-UVB在活动性疾病中诱导稳定性和产生色素沉着方面比PUVA更有效。此外,最近的一项荟萃分析指出,长期使用NB-UVB(12个月)可产生最高(> 75%)的褪色率。面部和颈部的色素沉着最大,其次是躯干和四肢。髋骨区域没有显示出> 75%的色素沉着。通过添加局部维生素D3类似物或局部钙调神经磷酸酶抑制剂,除面部和颈部外,对NB-UVB的大于50%和75%的色素沉着反应没有明显改变[ 83 ]。
发展期可以小剂量照光
一定严格按照说明操作 反正我是发展期照光的,并且效果还不错,所以我认为不耽误
论坛的方法是病友总结出来的,个人比较认可。
掌握好剂量发展期也可以照光的。 主要还是怕发展期掌握不好剂量。 发展期308激光的话可以直接照,uvb的话建议控制一个月以后开始照
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