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Segmental vitiligo is unique, even beyond the fact that it doesn’t cross the midline. It spreads very quickly, faster than the other forms, but only for about 6 months (sometimes up to a year). It’s such a rapid pace that patients assume it will soon cover their entire body, but it stops abruptly and usually remains stable, without changing, forever after that. Segmental vitiligo also frequently turns the hair white in the affected spot pretty quickly, which is important because vitiligo spots with white hair usually don’t respond very well to treatment. That’s because the melanocyte stem cells, which can make more of the pigment-making cells, live in the hair follicles, but are most likely destroyed if the hair has become affected by vitiligo, turning white.
Based on this, you can imagine that segmental vitiligo doesn’t respond well to treatments unless they’re started very early, before the hair is affected. That’s the bad news about segmental vitiligo. Of course, the good news is that “what you see is what you get” after about 6 months, it doesn’t commonly spread to affect other areas after this. There are exceptions, of course, which I’ll talk about below (that’s called mixed vitiligo). The other piece of good news is that segmental vitiligo is very responsive to surgical therapy called the melanocyte-keratinocyte transplant procedure (MKTP), described in detail here. In fact, MKTP is often a cure for segmental vitiligo!
就像John E. Harris博士提到的，节段形白癜风，发展迅速，通常6-12个月稳定，对药物反应不佳，对手术反应好。（查看了一下外文文献，很多都说SV是神经发布错误信号导致，跟寻常形白癜风有区别。）
来源：https://www.umassmed.edu/vitiligo/blog/blog-posts1/2020/05/patterns-of-vitiligo/
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发表于 2022-9-16 15:06:10
楼主